Abstract
In secret laboratories various synthetic or semi-synthetic amphetamine-type stimulants (ATS) are produced and processed. Stimulants of the form of amphetamine (ATS) are the second most common illegal drugs used worldwide, following cannabis. ATS production has increased worldwide, particularly from the Middle East. Fenethylline (CaptagonTM), a derivative of amphetamine, is commonly marketed as a street drug. Objective: this research aimed at applying gas chromatography / mass spectrometry (GC / MS) for fenethylline profiling of confiscated samples from the Saudi market. Methodology: The study of GC / MS was conducted on a general-purpose column (30 mm 0.25 mm i.d) filled with 0.25 mm cross bond, 5% diphenyl dimethyl polysiloxane (Rtx-5MS). The mass was worked in the process of impacting the electron. Results and discussion: Analyzed samples showed positive results for amphetamine in concentrations ranging from 0.07 to 43.02 percent of the substance in 60 percent of the samples. Caffeine was also present in 60 per cent of the samples at levels between 0.61 and 60.31 per cent. In the MS of the other active compounds were recorded in different proportions. Lastly, the presence of other substances in fenethylline samples may contribute to intoxication.
Highlights
amphetamine-type stimulants (ATS) are synthetic compounds belonging to the central nervous system (CNS) stimulant class to produce adrenaline-like effects such as amphetamine, methamphetamine, fenethylline, methylphenidate and dextroamphetamine [1,2]
Objective: this research aimed at applying gas chromatography / mass spectrometry (GC / MS) for fenethylline profiling of confiscated samples from the Saudi market
A simple and rapid method for direct separation and determination of a range of CaptagonTM in GC – MS seized tablets is described in this report
Summary
ATS are synthetic compounds belonging to the central nervous system (CNS) stimulant class to produce adrenaline-like effects such as amphetamine, methamphetamine, fenethylline, methylphenidate and dextroamphetamine [1,2]. ATS are the second most commonly used illicit drugs worldwide after cannabis. In secret laboratories various synthetic or semi-synthetic amphetamine-type stimulants (ATS) are produced and processed. Stimulants of the form of amphetamine (ATS) are the second most common illegal drugs used worldwide, following cannabis. Fenethylline (CaptagonTM), a derivative of amphetamine, is commonly marketed as a street drug. Objective: this research aimed at applying gas chromatography / mass spectrometry (GC / MS) for fenethylline profiling of confiscated samples from the Saudi market. The presence of other substances in fenethylline samples may contribute to intoxication
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