Abstract
AimTo profile the bioactive compounds present in methanolic extract of Sargassum tenerrimum by Gas Chromatography–Mass Spectrometry (GC–MS) analysis for its antibacterial activity. MethodsAntibacterial activity of methanolic extract was evaluated against five pathogenic strains by disk diffusion method at different concentration (25, 50, 75 and 100 μg/ml). ResultsThe presence of bioactive functional groups was revealed by Fourier Transform-Infrared Spectrophotometer (FT-IR) analysis. The identification of phytocomponents of the methanolic extract was done by Gas Chromatography–Mass Spectrometry analysis. Twelve compounds were identified of which two compounds 1, 2-Benzoldicarbonsaeure and Cyclopropanepentanoic acid showed maximum intensity of peak. The methanolic extract showed good antibacterial activity against five pathogenic strains at different concentration. ConclusionTo conclude, S. tenerrimum was found to have bioactive compounds and it is necessary to identify the compounds responsible for antibacterial activity.
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