GC-MS Analysis of Momordica charantia and Momordica dioica Fruit and Root Methanolic Extracts

Abstract

The present paper reports the GC-MS analysis studies of Momordica charantia and Momordica dioica Fruit and Root methanolic extracts. An attempt is made to analyze comparatively for the presence of similar compounds with biological activity in both the plants, to assess the chemotaxonomic relationship between these two plants. These two plants are perennial, rhizomatous, climbers belonging to cucurbitaceae family. These are seasonal vegetables of high demand and medicinal plants in Asian countries. Momordica charantia is indigenous and because of its higher medicinal importance it is also cultivated throughout the world. There is a growing demand for fruit and roots of Momordica charantia and Momordica dioica in the pharmaceutical trade due to their usage as medicinal agents for anti-inflammation, degenerative diseases including atherosclerosis, ischemic heart disease, ageing, diabetes mellitus, cancer, neurodegenerative diseases and others. In the present study fruit and roots of Momordica charantia and Momordica dioica were sequentially extracted by methanol and GC-MS analysis is carried for the extracts separately. The extracts showed the presence of many phytoconstituents reported in these plants. The GC-MS analysis of the methanolic extract revealed the presence of many similar major compound like plamictic acid with antidiabetic property is identified in both fruit and root methanolic extracts of Momordica charantia and Momordica dioica . This study forms a basis for the biological characterization and importance of the compounds identified.