Abstract
MasfonAloe veradrink was employed in this study to ascertain its effect on gastric acid secretion, mucus output and cytoprotection. The study utilized forty five (45) wistar albino rats which were dividedinto 3 batches of 15 rats each. Batch 1 served for gastric acid secretion, while batches 2 and 3 were for mucus output and cytoprotection studies respectively. Each batch was further divided into three groups of 5 rats each (control, low dose and high dose). The study duration was 21 days. The control received 0.3 ml of normal saline (0.9% NaCl solution) while the low dose (LD) and high dose (HD) experimental groups received Masfon-Aloe veradrink (1 ml and 3 ml/kg body weight orally, once daily respectiv ely). The study was done at the Department of Physiology, University of Calabar, Nigeria. Results showed the mean basal gastric acid output (µmol/L/hr) for both low dose (9.92±1.51) and high dose (13.36±1.25) groups were significantly (P<0.01 and P<0.001) greater than control (5.20±0.05). Following histamine administration, the mean gastric acid output in the experimental groups were, control (21.64±3.58), low dose (24.64±2.76), and high dose (19.60±1.93). Simultane ous
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
