Abstract
Liver cirrhosis tends to increase the risk in the management of gastrointestinal tumors. Patients with gastrointestinal cancers and liver cirrhosis often have serious postoperative complications and poor prognosis after surgery. Multiple studies have shown that the stage of gastrointestinal cancers and the grade of cirrhosis can influence surgical options and postoperative complications. The higher the stage of cancer and the poorer the degree of cirrhosis, the less the surgical options and the higher the risk of postoperative complications. Therefore, in the treatment of patients with gastrointestinal cancer and liver cirrhosis, clinicians should comprehensively consider the cancer stage, cirrhosis grade, and possible postoperative complications. This review summarizes the treatment methods of patients with different gastrointestinal cancer complicated with liver cirrhosis.
Highlights
Gastrointestinal cancers and liver cirrhosis are common diseases worldwide
We summarize the treatment for patients with different gastrointestinal cancers complicated with liver cirrhosis and focus on the analysis on the influence of different grades of liver cirrhosis on the treatment and postoperative complications, aiming to provide guidance for treatment options for patients with gastrointestinal cancers and liver cirrhosis
Horiki et al reported in a retrospective cohort study that four patients with gastric cancer and cirrhosis received endoscopic mucosal resection (EMR), with no patients died of the cancer and no postoperative complications occurred in the 10-year follow-up period
Summary
Gastrointestinal cancers and liver cirrhosis are common diseases worldwide. A significant number of patients with gastrointestinal cancer suffer from liver cirrhosis. Patients with mild cirrhosis can receive most cancer treatments without serious postoperative complications, while patients with severe cirrhosis can only be treated conservatively. Horiki et al reported in a retrospective cohort study that four patients with gastric cancer and cirrhosis received EMR, with no patients died of the cancer and no postoperative complications occurred in the 10-year follow-up period.
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