Abstract
The aim of the work – conduct a literature review to study the most important and complex aspects in the diagnosis and treatment of gastroesophageal reflux disease that are encountered in the practice of a family doctor.Results. Gastroesophageal reflux disease is becoming an increasingly important disease for the young and able-bodied population, which gives it not only a medical, but also an economic aspect. This is one of the most common pathologies in the practice of not only a therapist, family doctor and gastroenterologist, but – due to the presence of extraesophageal manifestations – in a wider range of medical specialties. Since gastroesophageal reflux disease has many “masks”, this leads to delayed diagnosis and treatment. This disease does not have a “gold standard” in routine diagnostics, and the presence of its refractory forms leads to treatment failures and complications. With a comorbid course of gastroesophageal reflux disease, both diagnosis and treatment require an integrated approach.Conclusions. Gastroesophageal reflux disease remains one of the most common diseases in the practice of a family doctor. Despite the extensive study of this pathology, it continues to remain difficult in terms of diagnosis and treatment, which is associated with the presence of extraesophageal manifestations, comorbid and refractory course. This requires an additional study of pathogenetic mechanisms and the development of therapeutic and diagnostic measures on the basis of this
Highlights
At the moment, gastroesophageal reflux disease (GERD) is the most common pathology among diseases of the digestive system, and among diseases of the esophagus its share is 75 % [1]
Rejuvenation of the pathology may lead to an increase in the number of complications such as Barrett's esophagus and adenocarcinoma [11] due to a longer history, which entails a longer treatment with proton pump inhibitors (PPIs)
It has been shown that 91 % of the alleles that increase the risk of GERD increase the risk of Barrett's esophagus and / or adenocarcinoma, which significantly expands the possibilities of detecting genes for these traits [15]
Summary
Gastroesophageal reflux disease (GERD) is the most common pathology among diseases of the digestive system, and among diseases of the esophagus its share is 75 % [1]. Has a steady upward trend [3], annually increasing by 5 % With this disease there is a significant decrease in the quality of life [4], patients are in fifth place after hypertension, menopause, angina pectoris and peptic ulcer disease [3]. A particular difficulty in the problem of GERD is the presence of comorbid pathology, which, on the one hand, changes the clinical course of GERD, and on the other, is often masked as extraesophageal manifestations of this disease. All this contributes to the underdiagnosis of comorbid pathology in GERD. The aim of the work – to review the literature to study the most important and complex aspects in the diagnosis and treatment of gastroesophageal reflux disease, which occur in the practice of family medicine
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
