Gastroesophageal devascularization for the treatment of cirrhotic portal hypertension

Abstract

Objective To evaluate the therapeutic effect of gastroesophageal devasculariztion on cirrhotic portal hypertensive bleeding. Methods Clinical data of 85 cirrhotic patients with portal hypertentsive bleeding undergoing gastroesophageal devascularization were retrospectively analyzed. Results The following-up rate was 78％. The 1-yr,3-yr and 5-yr survival rate was 95％, 88％ and 82％respectively.There was significant difference in survival time after devascularization between patients of Child-Pugh A and Child-Pugh B.For the whole group the 1-yr,3-yr and 5-yr recurrent bleeding rate was 6％,16％ and 28％ and postoperative hepatic encephalopathy was 7％.ALT,AST and ALB recovered to pre-operative level on post-operative day 7. Conclusions Gastroesophageal devascularization was an effective therapy in treating portal hypertensive variceal bleeding.Liver function remains a significant factor influencing long term survival. Key words: Hypertension, portal; Liver cirrhosis; Esophageal and gastric varices; Devascularization