Gastroenterological masks of chronic yersiniosis in children: comprehension of experience

Abstract

Chronic yersinioses are “therapeutic” infections with predominant symptoms of a somatic pathology while the typical manifestations of the infectious process are absent. Рurpose . Тo analyze the features of clinical manifestations of chronic yersinioses in children and to evaluate the eff ectiveness of diagnostic methods for detecting the disease. Characteristics of children and research methods. Laboratory confi rmation of the diagnosis of yersiniosеs was the criterion for including patients in the study group. As a result the group of patients with chronic yersiniosis infection included 131 children, 68 boys and 63 girls aged 2 years 8 months to 17 years 11 months (the average age of the group was 10 years) with typical gastroenterological pathology Laboratory confi rmation of the diagnosis of pseudotuberculosis and intestinal yersiniosis was carried out using the PCR to detect pathogenic yersinia in feces, specifi c antibodies were determined by a set of methods. Results . The article describes the clinical variants of chronic yersiniosis infections in children caused by Yersinia pseudotuberculosis and pathogenic Yersinia enterocolitica. Мost organs of the gastrointestinal tract (stomach, pancreas, liver, small and large intestines, mesenteric lymph nodes) can be aff ected in the course of chronic yersiniosis infection in children. A recurrent course of chronic yersiniosis infection is possible in children with hypogammaglobulinemia A. Conclusion . The chronic yersinioses can be suspected in the absence or insignifi cant eff ect of standard therapy of somatic pathology (gastritis, pancreatitis, irritable bowel syndrome, functional dyspepsia, etc.). The irritable bowel syndrome and functional dyspepsia are most common clinical variants of chronic yersiniosis infection in children. The immunoblotting is the most effective method to confi rm the diagnosis of chronic yersinioses.