Abstract

1. Gastrin/cholecystokinin-like peptides have been detected in the juveniles of Pecten maximus. 2. For the first time, positive immunocytochemical reactions have been observed in nervous tissue, neurosecretory cells of the cerebral ganglia, and digestive tissues: gastric shield and digestive gland. 3. Radioimmunoassays have demonstrated the presence of G/CCK material in the haemolymph; this suggests a neuroendocrine secretion of this peptide. 4. Heterogeneity of the G/CCK immunoreactive material was shown after molecular sieving of crude extracts of the three tissues. 5. A high molecular weight peptide was found to be present in ganglia and stomach, while only small peptides were common to the ganglia, stomach and haemolymph. 6. After a test meal, an increase of the G/CCK material has been noted in total extracts of Pecten maximus juveniles. 7. Such variations suggest a role of these substances in the regulation of molluscan digestive processes.

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