Abstract
Abstract: We report a case of hemorrhagic gastric ulcer in which endoscopic injection of Histoacryl effectively achieved hemostasis. The patient was an 86‐year‐old woman with complaints of hematemesis and melena, and emergent endoscopic examination revealed fresh bleeding from the gastric ulcer. Neither endoscopic injection of Aethoxysklerol and ethanol nor clipping stopped the active bleeding, while the injection of Histoacryl produced an immediate hemostatic effect. Unfortunately, she died of pneumonia and heart failure seven days after this treatment. Autopsy revealed Histoacryl polymer localized in the gastric wall, but the gastric ulcer that had caused the massive bleeding was covered with exudate and the site of arterial rupture was unclear. The significant hemostatic effect of Histoacryl injection and the histological findings in this case suggest that this procedure may be useful for managing refractory hemorrhagic gastric ulcer.
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