Abstract

Abstract During routine studies of oesophageal motility the lowest pH recorded from the stomach has been measured by a stomach electrode on 263 separate occasions. The mean pH of 117 male patients with duodenal ulceration was 1.3 ± 0.3 (mean ± 1 standard deviation), and this was lower than in 17 patients with a gastric ulcer (1.7 ± 0.3) and 19 with a hiatal hernia (1.6 ± 0.4). Patients with a gastric ulcer had a lower pH than those with gastric carcinoma (2.3 ± 0.9). The lowest pH of duodenal ulcer patients was changed by truncal vagotomy (37 patients) to 1.3 ± 0.8 and by a Polya partial gastrectomy (25 patients) to 3.2 ± 1.8. If a stomal ulcer was present after a partial gastrectomy the pH was 1.1 and this changed to above 1.9 after vagotomy.

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