Abstract
Gastric carcinosarcoma with rhabdomyosarcomatous differentiation is a rare tumor. Herein, we report the case of a 34-year-old man with a history of dysphagia, upper abdominal fullness, and poor appetite. Endoscopic findings showed a large friable mass that originated from the gastric cardia and lesser curvature of the high body. Consequently, radical total gastrectomy with Roux-en-Y esophagojejunostomy was performed. Histopathological analysis of the resected specimen revealed that the mass had invaded the serosa without regional lymph node metastasis; moreover, the tumor was positive for desmin and myogenin. Finally, we conclude this report with literature review and discussion.
Highlights
Carcinosarcoma is an uncommon biphasic malignant tumor composed of carcinoma and sarcoma components
Histopathological analysis of the resected specimen revealed that the mass had invaded the serosa without regional lymph node metastasis; the tumor was positive for desmin and myogenin
Abdominal computed tomography (CT) revealed an irregular lobular mass, measuring approximately 7.5 × 6.5 × 8.5 cm3, stretching from the esophagogastric junction (EGJ) to the lesser curvature of the gastric high body, with at least three enlarged regional lymph nodes around the EGJ and lesser curvature of the stomach (Figure 2A, 2B)
Summary
Carcinosarcoma is an uncommon biphasic malignant tumor composed of carcinoma and sarcoma components. ABSTRACT Gastric carcinosarcoma with rhabdomyosarcomatous differentiation is a rare tumor. We report the case of a 34-year-old man with a history of dysphagia, upper abdominal fullness, and poor appetite.
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