Abstract

The goal of this study is to describe the distribution of gastric cancer by age, gender, duration of symptoms, nutritional status and staging of the disease based on operative findings and correlation between the data. This was an observational study. The study was conducted at Department of Surgery, Nepal Medical College Teaching Hospital from December 2012 to December 2017. All patients who were admitted to the department with a diagnosis of stomach cancer and underwent palliative or curative intent procedure were reviewed and analyzed. Out of the 80 patients, 51(63.7%) were male and 29 (36.3%) patients were female. The disease was commonest in the 6th and 7th decades of life. Majority of the patients were of Tibetoburmese (Mongolian) origin with 44 (55%). Majority of patients, 60 (75%) patients had long duration of illness of more than 6 months. Most of the patients had albumin level less than 3gm/dl. Gastric carcinoma is a male predominant malignancy usually of old age and commonly observed in the Tibeto-Burman group of people. Overwhelming majority diagnosed at an advanced stage and had poor prognosis.

Highlights

  • Gastric cancer remains the fourth most common type of cancer and is the second leading cause of cancer-related death worldwide.[1]

  • There is a growth of stomach cancer in Nepal in certain populations, more commonly afflicted are the lower socioeconomic classes due to increase in incidence of Helicobacter pylori bacteria in these group of people.[2]

  • For example in a study conducted by Merchant SJ et al disparities in gastric cancer shows clear disparities between hispanics, asian and white communities in descending order.[6]

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Summary

Introduction

Gastric cancer remains the fourth most common type of cancer and is the second leading cause of cancer-related death worldwide.[1]. There is a growth of stomach cancer in Nepal in certain populations, more commonly afflicted are the lower socioeconomic classes due to increase in incidence of Helicobacter pylori bacteria in these group of people.[2]. The incidence rate in men is double that of women and incidence increases with age.[3,4] Even within the same geographic region certain ethnic groups have significantly higher risk of disease.[3] According to the present data from Nepal, it is the 5th commonest cancer including both genders, 3rd in males and 6th in females.[4] Endoscopic biopsy is widely regarded as the most sensitive and specific diagnostic tool for gastric cancer.[5] Currently, the only potentially curative treatment for gastric cancer is surgery with adequate lymph node dissection

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