Gastric Arrhythmia and Nausea of Motion Sickness Induced in Healthy Japanese Subjects Viewing an Optokinetic Rotating Drum

Abstract

The purpose of this study was to investigate whether nausea or gastric dysrhythmia, including tachygastria, which was determined by electrogastrography (EGG), were observed during optokinetic motion sickness in healthy Japanese volunteers. Twelve volunteers (9 men and 3 women) participated in the study. The subjects were asked to sit in a chair with their heads positioned in the center of a drum whose inside had been painted with black and white stripes. After a 15 min resting period, the drum was rotated at a speed of 60 degree/sec for 15 min. The EGG was continuously recorded for a total of 45 min (15 min resting period, 15 min rotation period, and 15 min recovery period). The severity of nausea was evaluated with a visual analogue scale (VAS) before, immediately after, and 15 min after the cessation of drum rotation. Other motion sickness symptoms were evaluated by scores of subjective symptoms of motion sickness (SSMS). Of 12 subjects who completed the study, 10 complained of nausea immediately after cessation of drum rotation. The VAS score for nausea immediately after the drum rotation period and 15 min after cessation of the rotation was significantly higher than during the resting period. The EGG during the drum rotation period showed a decrease in normogastria, which was accompanied with an increase in tachygastria. We conclude that gastric tachyarrhythmia and nausea may be induced by viewing an optokinetic rotating drum in healthy Japanese subjects who may have a hypersusceptibility to vection-induced motion sickness. The gastric dysrhythmia obtained with EGG could be a useful observation to support the appearance of nausea induced by optokinetic motion sickness.