Gastric and small intestine gastrointestinal stromal tumors: our experience

Abstract

Background: Gastrointestinal stromal tumors (GIST) are rare, although their incidence has increased in recent years. They are characterized by presenting a mutation in the c-Kit gene (CD117). The most common location is the stomach, followed by the small intestine and less frequently in the large intestine, esophagus, and mesentery. The main prognostic factors are the mitotic index and tumor size, and the main treatment is surgical resection. The spread is mainly hepatic and peritoneal. The objective of this study is to present our departments’ experience in the surgical treatment and long-term outcomes of GIST tumors in the stomach and small intestine.