Abstract
Gas therapy is actually drawing attention in nanomedicine as a safe and therapeutically efficient technique. Indeed, the design of stimuli-responsive nanocarriers with controlled release is encouraging to heal without any risk of gas poisoning. Here, we review recent developments of gas nanogenerators and gas-releasing molecules for controlled and targeted gas therapy in cancer nanomedicine. We present gases used in anticancer therapy, such as hydrogen, carbon dioxide, sulfur dioxide, hydrogen sulfide, oxygen, carbon monoxide, and heavy gases. The construction of gas nanogenerators and gas-releasing molecules with unique biological and physicochemical properties has allowed targeted and controlled release of gas molecules. We describe the stimulation method for each gas, along with gas nanogenerators and gas-releasing molecules.
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