Abstract
The mixing of inspired gas with that already present in the lung is brought about by gaseous diffusion. It has been generally accepted that this process is sufficiently rapid as to leave no appreciable concentration gradient (stratified inhomogeneity) within the lung during quiet respiration. The shape of the alveolar plateau has therefore been explained on the basis of regional inhomogeneity. A theoretical analysis of diffusion within the lung airways has been made involving the validation of a model suitable for analysis and at the same time being compatible with anatomical information A variety of models have been analysed and criticised, and from the analysis the conclusion has been drawn that stratified inhomogeneity within the lung is likely, and plays a part in the formation of the alveolar plateau.
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