Abstract

Abstract Gas-liquid chromatographic separation of the optical isomers of norephedrine, norpseudoephedrine, ephedrine, pseudoephedrine, N-ethylnorephedrine and N-ethylnorpseudoephedrine by means of their N-trifiuoroacetyl-L-prolyl derivatives has been investigated. A quantitative determination of the enantiomeric percentages was possible for the primary amines, and for all secondary amines except pseudoephedrine. The method is suitable for metabolic studies.

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