Abstract

Abstract Salicylamide, acetaminophen, and caffeine in drug formulations can be separated and quantitatively measured by GLC. Amobarbital and cyclizine are used as internal standards; the 4’ GLC column contains 3% OV-17 on Gas Chrom Q. The signal from the KCl thermionic detector is amplified and fed directly into the analog-to-digital converter of a PDP 12A LINC System computer. Results by the computer are compared to manual peak height measurements for 6 commercial preparations injected in duplicate and to results obtained from a UV procedure.

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