Abstract
BackgroundGanoderma spore is a minuscule germ cell ejected from Ganoderma gills during its growth maturity period, it has been considered with high exploitable potential in health-care products manufacture.MethodsAfter testing sporoderm-broken rate, the triterpenoids in 12 batches of broken and unbroken Ganoderma spore powder (GSP) samples were compared with Ganoderma lucidum fruiting body (GL) by high performance thin-layer chromatography (HPTLC) and further verified by liquid chromatography coupled with electrospray ionization quadrupole-time-of-flight mass spectrometry (LC–QTOF–MS); meanwhile, the dissolution of triterpenoids after bionic extraction was also investigated by HPTLC.ResultsThe sporoderm-broken rate of all the broken GSP samples was over 85%. The relative peak area of triterpenoids in GSP samples were lower than 50% of that in fruiting body, and the dissolution of triterpenoids in artificial gastrointestinal fluid was lower than in methanol.ConclusionsThis study demonstrated that there were little triterpenoids in GSP. Triterpenoids in GSP also seldom be dissolved in artificial gastrointestinal fluid.
Highlights
Ganoderma spore is a minuscule germ cell ejected from Ganoderma gills during its growth maturity period, it has been considered with high exploitable potential in health-care products manufacture
The sporoderm-broken rate of all the broken Ganoderma spore powder (GSP) samples was over 85% (Table 1), it could be considered that all the broken GSP samples were broken completely
Filiform mycelia could not be observed in the samples, which meant that there was no fruiting body powder mixed into GSP samples
Summary
Ganoderma spore is a minuscule germ cell ejected from Ganoderma gills during its growth maturity period, it has been considered with high exploitable potential in health-care products manufacture. Triterpenoids are the main active ingredients in Ganoderma and one of the Chinese Pharmacopoeia markers, which have anti-viral, anti-tumor and anti-inflammatory activities [6, 7]. Ganoderma spore is a minuscule germ cell ejected from Ganoderma gills during its growth maturity period. Spore has two very hard chitin spore walls which make the internal activity components difficult to be absorbed and digested in human gastrointestinal tract. In order to improve the utilization of Ganoderma spore powder (GSP), it is essential to break spore walls.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
