Abstract

Although ganglioneuromas are benign and easily recognizable tumors, primitive neural tumors of the adrenal gland, such as neuroblastoma, are malignant and present much more complex problems in diagnosis and classification. Ganglioneuromas may occur in a variety of sites, including the adrenal gland. They are benign neural tumors composed of ganglion cells and Schwann cells. Neuroblastomas are malignant tumors derived from primordial neural crest cells. These tumors may be identified in a variety of sites, including the adrenal gland. Neuroblastomas usually are sporadic. They are the fourth most common malignant tumor in children; most occur in children younger than 5 years, and one fifth are congenital.

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