Abstract
Composites of Silver nanoparticles/chitosan were obtained in aqueous solution, in-one step and eco-friendly synthesis, under ambiental conditions, using gamma irradiation. The radiochemical synthesis enabled obtaining of controlled size, monodisperse and high stability Silver nanoparticles. The obtained composites presented UV-Vis surface plasmon resonance comprised between 406-414 nm, depending on composition of the reactant system, spherical shape and narrow particle size distributions, with mean dimensions between 3-55 nm, and good antibacterial properties proven against Staphylococcus aureus and Escherichia coli. The influence of the Silver ions/chitosan ratio and of the pH of the initial solution on the final Ag Np properties is also discussed.
Highlights
IntroductionDue to their peculiar properties related to their high specific area, colloidal systems of Silver nanoparticles (Ag Np) have a wide range of applications, such as catalysts, sensors and biosensors, pharmaceuticals (e.g. diagnostics, drug delivery or tumoral therapies), electric and electronic devices a.s.o
Due to their peculiar properties related to their high specific area, colloidal systems of Silver nanoparticles (Ag Np) have a wide range of applications, such as catalysts, sensors and biosensors, pharmaceuticals, electric and electronic devices a.s.o
Recent studies shown that Ag Np are highly efficient against different microbial agents such as fungi, bacteria, viruses [4,5,6], opening new ways for development of new Ag Np based materials for biomedical applications, of great importance in the current global pandemic context caused by the spread of SarsCoV-2
Summary
Due to their peculiar properties related to their high specific area, colloidal systems of Silver nanoparticles (Ag Np) have a wide range of applications, such as catalysts, sensors and biosensors, pharmaceuticals (e.g. diagnostics, drug delivery or tumoral therapies), electric and electronic devices a.s.o. Recent studies shown that Ag Np are highly efficient against different microbial agents such as fungi, bacteria, viruses [4,5,6], opening new ways for development of new Ag Np based materials for biomedical applications, of great importance in the current global pandemic context caused by the spread of SarsCoV-2. In contrast with the conventional methods, the radiochemical synthesis takes place in one-step and under mild conditions of temperature and pressure, leading to well dispersed systems with narrow particle size distribution and does not involve the use of chemical toxic reduction agents nor waste release, being considered an eco-friendly method of synthesis. The dimensional control of nanoparticles can be achieved by varying a small number of synthesis parameters, especially by controlling the irradiation dose [12, 13]
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