Abstract
Brainstem gliomas, accounting for only 2% of adult brain tumors, constitute 10% to 20% of central nervous system tumors in the pediatric group [3]. They are mainly located in the mesencephalon, the pons (including the cerebellar peduncles), and the medulla oblongata. In pediatric patients, a thorough neurological examination and magnetic resonance (MR) imaging are essential in the establishment of the diagnosis, treatment plans, and therapeutic approaches with or without biopsy [1, 12]. Some case series had proved the therapeutic effect of Gamma Knife radiosurgery (GKS) to brainstem gliomas [4, 8, 15]. For pediatric patients, however, long-term adverse effects caused by radiation injury are always the main concern. In this report, we reviewed our long-term follow-up experience of two pediatric cases with brainstem gliomas after GKS treatment.
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