Gamma Knife Extend Noninvasive Fractionated Radiosurgery: A Novel Technique for the Treatment of Skull Base Lesions

Abstract

Object: The Gamma Knife Extend system is designed for noninvasive fractioned radiosurgery. Such a system theoretically allows clinicians to use radiosurgery for larger volumes and targets near eloquent areas and re-treatments, which were previously not possible in a single fraction. Here we describe the Washington University initial clinical experience with dose, fractionation, patient setup, and outcomes.