Abstract
Gamma aminobutyric acid (GABA) receptor agonists have shown to be effective in reducing infarct size and improving functional outcome in animal models of cerebral ischemia. However, the sedation effects of GABA receptor agonists limited the application in acute stroke patients because of the potential risk of stupor. ### Objective The aim of this study is to determine the efficacy and safety of GABA receptor agonists in the treatment of acute stroke. ### Types of Studies Randomized controlled trials. ### Types of Participants Acute stroke patients within 12 hours after stroke onset. ### Types of Interventions GABA receptor agonists in …
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