Abstract

The Human Fertilisation and Embryology Authority and its predecessors have restricted the maximum number of oocytes and embryos that can be transferred in gamete intrafallopian transfer and in vitro fertilisation to minimise the risk of multiple pregnancy. The current maximum of three practically eliminates the risk of quadruplet or higher order pregnancies. Women in their fifth decade have reduced fecundity and an increased risk of miscarriage after spontaneous or assisted conception.1, 2 Because of this and the current restrictions we are concerned that such women might use donor oocytes from young women to overcome infertility, although they might have an acceptable chance of pregnancy if a flexible number of their own oocytes could be used. We therefore retrospectively assessed the effect of the restrictions on the outcome of gamete intrafallopian …

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