Abstract

In order to study the recent incidence of gallstones or gallbladder cancer in autopsy cases, 103, 454 pathological autopsy cases from the Annual of the Pathological Autopsy Cases in Japan (1991-1993) in which autopsied stillborn infants, neonates, age-and sex-unknown cases were excluded, were subjected. Gallstones were detected in 2, 478 cases (2.4%) including 2, 204 cases (2.1%) of cholelithiasis, 268 cases (0.3%) of bile duct stones and 104 cases (0.1%) of intrahepatic gallstones. Cholecystectomy had been already performed in 187 cases (7.8%) among 2, 391 cholecystolithiasis. Gallbladder cancer was encountered in 1, 516 cases (1.5%), and 52 cases (9.3%) in men and 124 cases (13.0%) in women of them were complicated with cholecystolithiasis. On the contrary, the incidences of cholelithiasis associated with gallbladder cancer were 4.5% in men and 11.7% in women, totally 8.0%. Fifty-three cases (4.1%) of gallstones in men had intrahepatic gallstones and 51 cases (4.3%) in women. These percentages of intrahepatic gallstones were higher than those encountered in clinical cases. A ratio of man to woman in intrahepatic gallstones was 1 to 1.05, and there was no significant difference on incidence of intrahepatic gallstones between both sexes.

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