Galli-Galli Disease: A Rare Acantholytic Variant of Dowling-Degos Disease

I Viana,J Gomes,J Labareda

doi:10.1155/2011/703257

Abstract

Galli-Galli disease is a rare acantholytic variant of Dowling-Degos disease, with few cases reported in the literature. We describe a case of Galli-Galli disease and review the literature.

Highlights

Galli-Galli disease (GGD) is a very rare variant of the Dowling-Degos disease (DDD) with the histologic finding of focal acantholysis
Histopathologic examination of three biopsy specimens revealed digitiform epithelial downgrowths of the rete ridges, with hyperpigmentation of the basal layer confined to the tips of the rete ridges
In one of the biopsy specimens, we found acantholytic and dyskeratotic cells (Figure 2(b))

Summary

Introduction

Galli-Galli disease (GGD) is a very rare variant of the Dowling-Degos disease (DDD) with the histologic finding of focal acantholysis. It was originally reported by Bardach et al in 1982, who described the disease in two brothers and named it eponymically after this family [1]

Case Report

Discussion

F Pruritic papular rash of the flexural areas and reticulate pigmentation