Gallbladder Tumor Treated Through Chemotherapy: A Case Report

João Kleber De Almeida Gentile

doi:10.31031/gmr.2021.06.000630

Abstract

Gastroenterology Medicine & Research Gallbladder Tumor Treated Through Chemotherapy: A Case Report Emanuela Alves Delmondes1, Júlia Guimarães Pereira1, Lais de Campos Bento1, Mariana Mussalem Santos1, Natália dos Santos Ramalho Vieira1, Renato Migliore2, João Kleber de Almeida Gentile2*, Rodrigo Biscuola Garcia3, Pedro Marcos Santinho Bueno de Souza3 and Jose Cesar Assef4 1Graduate of Medicine in University City of São Paulo (UNICID), São Paulo (SP), Brazil 2Medical Professor of the Discipline of Digestive Surgery in University City of São Paulo (UNICID). Medical doctor and Resident Physician, Department of Digestive Surgery, Hospital do Servidor Público Municipal (HSPM-SP), São Paulo (SP), Brazil 3Medical doctor and Attending Physician, Department of Digestive Surgery, Hospital do Servidor Público Municipal (HSPM-SP), São Paulo (SP), Brazil 4Medical doctor and Chief, Department of Digestive Surgery, Hospital do Servidor Público Municipal (HSPM-SP), São Paulo (SP), Brazil *Corresponding author:João Kleber de Almeida Gentile, Medical Professor of the Discipline of Digestive Surgery in University City of São Paulo (UNICID). Medical doctor and Resident Physician, Department of Digestive Surgery, Hospital do Servidor Público Municipal (HSPM-SP), São Paulo (SP), Brazil Submission:August 02, 2021;Published: August 18, 2021 DOI: 10.31031/GMR.2021.06.000630 ISSN 2637-7632Volume6 Issue1

Highlights

Gallbladder cancer is a rare but highly malignant disease in countries such as India, Chile, and Japan, where it has a high mortality rate [1,2]
Once its diagnosis is usually tricky and at a late stage, there is the necessity of using neoadjuvant chemotherapy in advanced cases
We report the case of a 51-year-old man diagnosed with gallbladder cancer presenting liver invasion but no metastasis

Summary

Introduction

Gallbladder cancer is a rare but highly malignant disease in countries such as India, Chile, and Japan, where it has a high mortality rate [1,2]. We report a case of a patient with advanced gallbladder neoplasm undergoing chemotherapy treatment with cure of the primary disease. The diagnosis of undifferentiated gallbladder adenocarcinoma with hepatic invasion was considered, considering the patient initially inoperable and referred to the oncology for neoadjuvant treatment. With the consent of the patient chemotherapy with gemcitabine was introduced at the dose of 1000mg/m2 weekly for 3 weeks, followed by a rest of 1 week and the schedule was repeated on an outpatient basis. His serum CEA level decreased gradually, and at follow-up CT for re-staging performed 8 cycles later in June 2012, showed reduction of gallbladder and hepatic gallbladder injury. 6 years after the initial diagnosis, the patient presents with no evidence of tumor recurrence, with a serum level of CEA 2 [7]. being followed up every six months

Discussion

Findings

Conclusion