Abstract
Objective: To estimate the frequency of gallbladder perforation with conventional Monopolar Diathermy versus Harmonic scalpel in laparoscopic cholecystectomy.
 Study Design: Quasi-experimental study.
 Place and Duration of Study: Department of Surgery, Combined Military Hospital, Quetta Pakistan, from Sep 2018 to Sep 2019.
 Methodology: A total of 160 patients undergoing laparoscopic cholecystectomy for symptomatic gallstones were included in the study and were randomly allocated into two groups based on the surgical technique of dissecting gall bladder from the liver bed. In Group-A, Monopolar Diathermy was used, and in Group-B Harmonic scalpel was used. Frequency of gall bladder perforation and demographic details were recorded on predefined proforma.
 Results: In our study, mean age was 48.21±8.94 years and 49.14±9.31 years in Group-A and Group-B respectively. Comparison of Gallbladder perforation in both groups showed 17(21.25%) cases in Group-A and 5(6.25%) cases in Group-B, (p-value <0.001).
 Conclusion: In laparoscopic cholecystectomy, the frequency of gallbladder perforation with conventional monopolar diathermy is significantly higher compared to the harmonic scalpel.
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