Gall Bladder Visualization in Experimental Achylia

Abstract

Hines1 has reported 11 cases of Achylia gastrica in which the Graham test was done; these patients received the tetraiodophenolpphthalein intravenously. In most of these cases the gall bladder failed to visualize and in the others the shadow was reported as abnormal. Patients with absence of shadow showed visualization in some instances when HCl was given by mouth. More recently Davis and Talley2 have reported 20 cases of anacidity, in the majority of which they obtained good visualization although 9 of these cases presented clinical evidence of gall bladder disease. They gave the dye by mouth.To determine whether the absence of hydrochloric acid from the gastrointestinal tract was capable of interfering with gall bladder visualization, 5 dogs with pouches of the entire stomach (esophagoduodenal anastomosis) in which all of the gastric secretion drained to the outside were subjected to the Graham test. Tetraiodophenolphthalein, 0.18 gm. per kilo, was given intravenously and 10 to 12 hours later roentgenog...