Abstract

While intracerebroventricular injection of galanin (5 μg/rat) inhibited sexual behavior in experienced male rats - without producing any other locomotor or behavioral deficit -, injection of the galanin antagonist, galantide, by the same route (1 or 2 μg/rat) stimulated sexual behavior (improving arousal, motivation and performance indexes) and antagonized the effect of galanin. These data further suggest that galanin plays a physiological role in male sexual behavior.

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