Abstract

To date, the main two classes of clinically used contrast agents for magnetic resonance imaging (MRI) are soluble paramagnetic gadolinium chelates and superparamagnetic iron oxide particles. While iron oxides predominantly increase T2-relaxivity and thus provide negative contrast, gadolinium chelates are often requested as they increase T1-relaxivity and enhance positive contrast. As particulate contrast agents are preferable due to a more favorable signal-to-noise ratio, the goal of our present work was the development of poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles labeled with chelated gadolinium.

Highlights

  • Scientia Pharmaceutica an Open Access Journal by MDPIThe Austrian Pharmaceutical Society (ÖPhG) is affiliated with Scientia Pharmaceutica

  • The journal publishes high standard papers submitted by researchers of the respective and neighboured disciplines, allowing a broad overview, including nutritional sciences, hospital pharmacy, history of pharmacy, etc

  • Rapid Publication Accepted papers are immediately published online No Space Constraints, No Extra Space or Color Charges No restriction on the length of the papers, number of figures or colors High Visibility Coverage by Leading Indexing Services Emerging Sources Citation Index (ESCI - Web of Science), PubMed (NLM), Scopus, EMBASE (Elsevier), CAS Chemical Abstracts (ACS) and other databases

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Summary

Scientia Pharmaceutica an Open Access Journal by MDPI

The Austrian Pharmaceutical Society (ÖPhG) is affiliated with Scientia Pharmaceutica. Message from the Editor-in-Chief Scientia Pharmaceutica is a unique journal offering insight into the diverse fields of Pharmaceutical Sciences. One advantage of Scientia Pharmaceutica is that it covers a very wide scope, starting from pharmacobotany and pharmacognosy/pharmaceutical biology, through natural products/pharmaceutical/medicinal chemistry, analytics, pharmacology and pharmaceutical technology/drug development, to clinical studies and the practice of pharmacy. The journal publishes high standard papers submitted by researchers of the respective and neighboured disciplines, allowing a broad overview, including nutritional sciences, hospital pharmacy, history of pharmacy, etc.

Open Access Unlimited and free access for readers
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