Abstract
Gabapentinoids, pregabalin and gabapentin, are neuronal voltage-gated calcium channel inhibitors mainly prescribed for the treatment of partial epilepsy and neuropathic pain. Although their efficacy as first-line treatments for painful neuropathic conditions (and several non-neuropathic painful conditions) has been well established in general medical practice, their efficacy and prescription in Oral Medicine and Oral Surgery practice has received little attention so far. This didactic article, the first of a two-part series, aims to present the experience of a French tertiary orofacial pain clinic regarding the prescription of gabapentinoids in Orofacial pain conditions that fall within the scope of the oral surgeon's practice.
Highlights
Gabapentinoids, pregabalin and gabapentin, are a recent class of neuronal voltage-gated calcium channel inhibitors, mainly prescribed for the treatment of partial epilepsy and neuropathic pain
In 2010, the European Federation of Neurological Societies published guidelines regarding the pharmacological treatment of neuropathic pain and addressing the respective role of gabapentinoids in the pharmacological armamentarium [4]
The diagnoses that led to the prescription of gabapentinoids were painful neuropathies (41 patients), headaches (4 patients), jaw diseases (1 patient), ENT diseases (1 patient), oral diseases (1 patient) and myalgias (1 patient)
Summary
Gabapentinoid prescription in oral medicine and oral surgery practice. Part I À Experience from a French Orofacial pain clinic. Abstract -- Gabapentinoids, pregabalin and gabapentin, are neuronal voltage-gated calcium channel inhibitors mainly prescribed for the treatment of partial epilepsy and neuropathic pain Their efficacy as first-line treatments for painful neuropathic conditions (and several non-neuropathic painful conditions) has been well established in general medical practice, their efficacy and prescription in Oral Medicine and Oral Surgery practice has received little attention so far. This didactic article, the first of a two-part series, aims to present the experience of a French tertiary orofacial pain clinic regarding the prescription of gabapentinoids in Orofacial pain conditions that fall within the scope of the oral surgeon’s practice
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