G63(P) Disease pattern, bacteriological profile and outcome of childhood acute bacterial meningitis

Abstract

<h3>Aim</h3> To determine the disease pattern, etiological agents and outcome of childhood acute bacterial meningitis <h3>Study design</h3> Descriptive observational study. Place and duration of study The Children’s Hospital and Institute of Child Health, Lahore, from Jan, 2012 to Dec, 2012. Statistical analysis SPSS 16.0 version <h3>Results</h3> Out of 199 pateints 36% were female and 64% male. 68.4% were between 2 months and 1 year 26.6% were between 1.1 and 3 years 10% were between 3.1 and 5 years 97% presented with fever 87% with poor feeding 25% with fits 10% with crying 23% with altered conscious level 13% with signs of mniengeal irritation Vaccination was incomplete in 7% unvaccinated 45% and vaccinated 48%. <h3>Complications</h3> 1% had hydrcephalus, 0.5% had subdural effusions, 4.5% had motor loss 10% have seizures maximum no of deaths less than 1 year. Malnutrition was associated with deaths in 31% and csf culture positivity in 25% (Figures 1, 2, 3). <h3>Conclusion</h3> Maxium no of deaths in males under 1 year, 33% with malnutritiion, 25% with csf culture positivitity coagulase negative staph aureus and streptoccoccus pneumnia were two most commoon pathogens in culture. Mortality under one year was maximun and associated with streptococcus pneumonia.