G382 Outcome of interventional cardiac catheterization in infants weighing less than 2500 grams: a comparative study

Abstract

Purpose To evaluate the feasibility, efficacy and safety of interventional cardiac catheterization in infants weighing less than 2500 gm. Methods This prospective cross sectional study included all patients who underwent interventional cardiac catheterization through the first 60 days of life in the specialized Children Hospital (AbuElreesh), Cairo University between January 2015 and January 2018. The study group included patients less than 2500 grams, while the comparative group included patients weighing ≥2500 grams. Each adverse event was classified according to either a single domain of attributability i.e. catheterization, access, stent, balloon or ICU related or the seriousness i.e. major and minor. Results The study group included 37 patients with a mean weight of 2.35±0.13 Kg, while the comparative group included 164 patients with a mean weight of 3.54±0.71 Kg. Four different procedures were included; Balloon atrial septostomy, pulmonary balloon valvuloplasty, PDA stenting and radiofrequency perforation for pulmonary atresia. The overall incidence of complications was higher in neonates Conclusion Generally, interventional cardiac catheterization in infants weighing less than 2500 grams is associated with increased incidence of adverse events. PDA stent is associated with increased mortality in low birth weight infants while pulmonary balloon valvuloplasty in infants with critical pulmonary stenosis is associated with higher incidence of major complications but no significant increase in mortality rates.