Abstract

BackgroundPostnatal head growth failure is well recognised in very preterm infants (VPI), the largest deficit occurs at 3–4 weeks followed by some catch-up growth until 36weeks corrected gestational age (36wCGA)....

Highlights

  • Humidified High Flow Nasal Cannula Therapy (HHHFNC) therapy is a modality of non-invasive ventilation which provides humidified, warm, high flow oxygen (>2 litres per minute)

  • Following the conclusions drawn from this data, a further prospective study aim would be to demonstrate whether HHHFNC has superiority or non-inferiority to Continuous Positive Airway Pressure (CPAP) therapy

  • Postnatal head growth failure is well recognised in very preterm infants (VPI), the largest deficit occurs at 3–4 weeks followed by some catch-up growth until 36weeks corrected gestational age (36wCGA)

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Summary

Introduction

HHHFNC therapy is a modality of non-invasive ventilation which provides humidified, warm, high flow oxygen (>2 litres per minute). It has been proposed as an alternative to CPAP in maintaining children without the need for intubation and mechanical ventilation. Method A retrospective study analysing records of 27 paediatric patients treated with HHHFNC therapy who presented with bronchiolitis between September 2010 – March 2011. The paired t-test analyses demonstrated statistical significance for changes in values for interval of difference of pH (p value -0.016), respiration rate (p value-0.001) and heart rate (p value -0.00). Following the conclusions drawn from this data, a further prospective study aim would be to demonstrate whether HHHFNC has superiority or non-inferiority to CPAP therapy. Preventing Early Postnatal Head Growth Failure in Very Preterm Infants: The Randomised Controlled SCAMP Nutrition Study doi:10.1136/archdischild-2013-304107.181

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