Abstract
Background: Duchenne muscular dystrophy (DMD) is a devastating striated muscle disorder and skeletal muscle pathology was characterized by muscle necrosis, inflammation, and muscle regeneration at the early stage, but these tissues have been finally replaced by fibrosis and fatty infiltration. To evaluate the skeletal muscle involvement in dystrophin deficiency, magnetic resonance imaging (MRI) has been widely used, but standard T2 weighted imaging (WI) cannot discriminate necrotic changes from fatty infiltration.
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