Abstract

G N Ramachandran made several remarkable contributions to biophysics and structural biology over the course of his celebrated career. In a pair of seminal papers in 1971, he also laid the foundation for the technique of ‘Projection Reconstruction’ that has come to revolutionize medical imaging. It is now routinely employed in modern CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) scans. In this article, we review the salient features of this technique, that allows the ‘reconstruction of an object from its shadows’.

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