G-CSF receptor expression on neutrophils of healthy term and preterm neonates and in those with infection

Abstract

Background: Granulocyte colony-stimulating factor (G-CSF) has been shown to induce neutrophilia and to enhance mature effector neutrophil function. Whereas serum concentrations of G-CSF are high during infection, nothing is known about G-CSF receptor (G-CSF-R) expression on neutrophils of neonates.