FXIIIA polymorphism in a Japanese population: Occurrence of FXIIIA*4 allele

Abstract

AbstractThe FXIIIA polymorphism was studied in a Japanese population using agarose gel isoelectric focusing and agarose gel electrophoresis, combined with immunoblotting onto nitrocellulose membranes. The correspondence of patterns between the two methods was confirmed by two‐dimensional electrophoresis. A rare phenotype, FXIIIA 4–1, was detected in one individual besides the three common phenotypes FXIIIA 1, 2–1, and 2. This rare phenotype was identified with the originally reported FXIIIA 4–1 in Melanesians. Our results indicate the possibility that the FXIIIA*4 allele may be distributed widely in world populations.