Abstract

Neonatal brain injury (NBI) is a complex and challenging area of research and critical care. Advances in understanding and treating NBI are crucial for improving the long-term adverse neurological outcomes of the affected neonates. Future perspectives in NBI are focused on systematic antenatal education, personalized medicine and profiling, stem cell and neuroprotective therapies, biomarkers in biological fluids with an emphasis on multimodal biomarker panels, collaborative research projects and considerations regarding ethical issues. Although substantial efforts have been made recently to restrain NBI, its incidence is still high on a global scale. Therefore, future management of NBI will involve a multidisciplinary approach that integrates genetics, individualized therapy, and medical advancements, with particular attention to early detection and intervention. The ultimate goal is to reduce the prevalence of NBI and improve the affected neonates' long-term prognosis. It is critical to remember that this field of study is still being investigated, and it could be years before many of these advancements are widely applied in standard clinical practice.

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