Abstract

Nowadays the output—and rewards—of research are based almost entirely on published papers in scientific journals. Scientists in low-income and middle-income settings would like to conduct research for their populations according to their own concerns. They want to be in the frontlines of national and global communications about their country’s experiences. I recommend that properly trained clinical trial experts from developed countries should conduct some workshops on the design, conduct and ethical issues in clinical trials to terminate the research misconduct in developing countries.DOI: http://dx.doi.org/10.3126/nje.v1i2.5090 Nepal Journal of Epidemiology 2011;1 (2):44-46

Highlights

  • In most clinical trials patients are entered one at a time, so that their responses to treatment are observed sequentially

  • Clinical trials are commonly carried out these days and it forms important sources of information for the rational use of drugs

  • The investigators are forewarned about the protocol compliance

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Summary

Introduction

In most clinical trials patients are entered one at a time, so that their responses to treatment are observed sequentially. Clinical trials are commonly carried out these days and it forms important sources of information for the rational use of drugs. In this article authors would like to describe the use, rationale and suggestions for of monitoring the trials while the trial is in progress[2,3,4,5,6,7,8]. Investigators need to be warned to look out for such events in future patients.

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