Abstract
Multimodality monitoring of cerebral physiology encompasses the application of different monitoring techniques and integration of several measured physiological and biochemical variables into the assessment of brain metabolism, structure, perfusion and oxygenation status, in addition to clinical evaluation. Novel monitoring techniques include transcranial Doppler ultrasonography, neuroimaging, intracranial pressure, cerebral perfusion and cerebral blood flow monitors, brain tissue oxygen tension monitoring, microdialysis, evoked potentials and continuous electroencephalography. Multimodality monitoring enables the immediate detection and prevention of acute neurological events, as well as appropriate intervention based on a patient’s individual disease state in the neurocritical care unit. Simultaneous real-time analysis of cerebral physiological, metabolic and cardiovascular parameters has broadened knowledge regarding complex brain pathophysiology and cerebral hemodynamics. Integration of this information allows for a more precise diagnosis and optimization of management of patients with brain injury.
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