Abstract
ABSTRACTFuture Leader to Watch is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Olayemi Joseph Olajide is first author on ‘Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease’, published in BiO. He is a Research Fellow in the Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Quebec, Canada, investigating the mechanisms of molecular neurodegeneration during the pathogenesis of Alzheimer's disease.
Highlights
Olayemi Joseph Olajide of neurons within this medial temporal lobe structure may play a central role in the early memory loss that is associated with Alzheimer’s disease, surprisingly few studies have focused on understanding why the entorhinal cortex may be vulnerable to molecular neurodegeneration
What has surprised you the most while researching this review? substantial progress has been made in the studying of Alzheimer’s disease, it is astonishing how very little research has been done to understand the mechanisms of molecular neurodegeneration in the entorhinal cortex and how this contributes to early loss of neurons during Alzheimer’s disease
What is more interesting is that the progressive nature of the pathological changes that occur in the entorhinal cortex can serve as effective biomarkers that may aid prediction and diagnosis of Alzheimer’s disease long before its clinical manifestation, which is a crucial objective in Alzheimer’s research
Summary
Olayemi Joseph Olajide is first author on ‘Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer’s disease’, published in BiO. He is a Research Fellow in the Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montreal, Quebec, Canada, investigating the mechanisms of molecular neurodegeneration during the pathogenesis of Alzheimer’s disease.
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