Abstract

Objective: The a6b1 integrin is the putative binding site of the sperm fertilin in mouse oocytes (Almeida et al., 1995). Furthermore mouse that have been deleted from the tetraspan CD9-/- gene are infertile because of the oocyte’s membrane inability to fuse with that of the spermatozoa (Le Naour et al., 2000). We investigated whether these molecules could also be involved in human gamete interaction or not.

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