Abstract
The Sri Lankan Journal of Infectious Diseases (SLJID) is an open access, peer-reviewed, biannual journal published by the Sri Lankan Society for Microbiology (SSM). The Journal considers articles from all professional disciplines involved in the field of infectious diseases. The Journal has been in publication since 2011, is included in the DOAJ since 2018 and is a member of COPE since 2021. The SLJID practices a double-blind peer review policy. From 2022, the SLJID publishes accepted manuscripts online immediately after copy-editing, enabling rapid dissemination of scientific knowledge. The published articles are subsequently compiled into two issues in April and October. The SLJID does not charge any article processing or publication fee.
Highlights
The Fusarium species is a mold that can cause invasive and disseminated infections in severely immunocompromised patients, such as patients with prolonged or profound neutropaenia and Tcell mediated immunodeficiencies
We present two children with leukemia who presented with dermatological manifestations of fusariosis
We emphasize that fungal infections should be considered in the differential diagnosis of those with neutropaenia and dermatological manifestations
Summary
The Fusarium species is a mold that can cause invasive and disseminated infections in severely immunocompromised patients, such as patients with prolonged or profound neutropaenia and Tcell mediated immunodeficiencies. As the patient remained afebrile, his chemotherapy regime was continued Two weeks after his admission, the fever recurred, and the patient developed a skin rash. After taking blood for culture and omitting flucloxacillin and IV fluconazole, the patient was started on IV clindamycin 12mg/kg 6hourly, IV vancomycin 15mg/kg 8hourly and IV amphotericin B (liposomal) 3mg/kg daily. Patient 2 A 5 1⁄2 year old boy presented with relapsed acute lymphocytic leukaemia six months after completing chemotherapy On admission he was asymptomatic, but neutropaenic (ANC count 630/μL). Http://sljol.info/index.php/SLJID Vol 11, No 1, April 2021 where the antibiotics were changed to IV piperacillin-tazobactam 112.5 mg/kg IV every 6hours and IV amphotericin B deoxycholate 1mg/kg daily empirically after taking blood for bacterial and fungal cultures.
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