Abstract
AbstractA patient whose tuftsin‐activities of serum and PMN had been found to be deficient was reported in 1975 by us. After the elapse of 4.5—5.5 years, tuftsin‐activity in addition to chemotactic, bactericidal and NBT‐reducing activities of the the patient's PMN were investigated. The tuftsin and bactericidal activities against staphylococcus of the patient's PMN fell within the normal range. However, as to the NBT‐test and chemotaxis, the patient and her sister who had suffered from similar symptoms in infancy were found to have lower activities. In addition, the serum IgE level of the patient was slightly higher.It is obscure as to why the patient's tuftsin‐activity recovered to a normal level, although she has not received γ‐globulin therapy for 5.5 years.It is conceivable that the patient suffers from a dysfunction of PMN, but it is impossible at the present time to make a definite diagnosis.
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