Abstract

The dynamic oxytocin test and the chemical assay of serum oxytocinase were carried out in 426 pregnant women with the aim of predicting the date of labor. In cases in which the oxytocin dynamic test showed decreasing values or rising levels of oxytocinase, conservative procedure was followed. In the remaining cases labor was induced by means of Syntocinon. In the prenatal period oxytocinase levels show steady increase in 79.9 per cent of cases, while the values of the oxytocin test decrease in 87.2 per cent. Both situations were observed simultaneously in 76.6 per cent of cases. Prediction of the date of labor by this biochemical method is 9 times as accurate as the prediction based upon Naegele's rule.

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