Abstract
The term lymphoblastoma has been suggested by Mallory and defined by Viets and Hunter as a general term for lymphosarcoma, lymphadenoma, Hodgkin's disease, and lymphatic leukemia. Holmes (1) described lymphoblastoma as a progressive generalized disease, occurring at any age, in either sex, and involving any tissues of the body, although primarily it has its seat in the lymph nodes of the neck and the mediastinum. It is now generally admitted that although there are definite distinguishing characteristics in the clinical manifestations and the histology of lymphosarcoma, Hodgkin's disease, and lymphatic leukemia, there is considerable similarity in their pathogenesis. Thus Ewing (2) believes that mediastinal Hodgkin's disease furnishes a large proportion of cases terminating in lymphosarcoma. Levin (3), analyzing more than 500 cases, frequently found pathological evidence of both Hodgkin's disease and lymphosarcoma not only in the same patient but even in different areas of the same tumor. Warthin (4) repo...
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